Diabetes Insipidus: A Pragmatic Approach to Management

Diabetes insipidus--diagnosis and management.

Central diabetes insipidus (CDI) is the end result of a number of conditions that affect the hypothalamic-neurohypophyseal system. The known causes include germinoma/craniopharyngioma, Langerhans cell histiocytosis (LCH), local inflammatory, autoimmune or vascular diseases, trauma resulting from surgery or an accident, sarcoidosis, metastases and midline cerebral and cranial malformations. In r...

Diabetes Insipidus: A Review

Inappropriate secretion or action of serum antidiuretic hormone (ADH) is termed Diabetes Insipidus (DI), characterized by polyuria (defined as 24 hour urine output in excess of 40 ml/kg) and polydipsia [1]. As opposed to Diabetes Mellitus, where the urine is hypertonic and sweet (mellitus means honey in Greek), DI is defined as having urine that is hypotonic and bland, in the setting of polyuri...

Diabetes Insipidus

679 W E ARE PRESENTING the case histories of two children with diabetes insipidus, of particular interest because of the diversity of manifestations, the variance in etiology and the complexity of management. One patient was observed for a period of 3 years, with onset of disease at age 10 years; another was observed for a period of 8 years, with the onset of tile primary disease at 2 years and...

Diabetes insipidus secondary to hydrocephalus.

Sir, I note with interest the recent report by Dr Menzies et al. of a patient with cranial diabetes insipidus secondary to arrested hydrocephalus.1 In his discussion he did not identify any previously reported cases of diabetes insipidus secondary to hydrocephalus. I recently reported a patient with diabetes insipidus which developed after subarachnoid haemorrhage.2 In the discussion, I noted a...

Diabetes insipidus.